International Union for the Study of Social Insects (IUSSI2018), August 5-10, 2018 in Guarujá, Brazil.

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Bringing the honeybee blood-brain barrier into focus

Author(s):
Tyler Quigley, Tyler Quigley , Dr. Gro Amdam
Institution(s):
School of Life Sciences, Arizona State University, Tempe, Arizona; School of Life Sciences, Arizona State University, Tempe, Arizona ; School of Life Sciences, Arizona State University, Tempe, Arizona; Norwegian University of Life Sciences, Ås, Norway
A honeybee’s behavior is influenced by her nutritional status as well as the pesticides and parasites she comes into contact with throughout her life. Nevertheless, we do not know how endocrine signals and foreign chemicals enter the honeybee brain. Elucidating this pathway requires an exploration of the honeybee blood-brain barrier, the thin layer of glial cells that physically separates brain circuits from the surrounding hemolymph. Here, I share my never-before-seen 3D reconstructions of honeybee blood-brain barrier glial cells, describe how pesticide, parasites, and age influence barrier integrity, and discuss the role the barrier may play in modulating pro-social signals between body and brain.
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