International Union for the Study of Social Insects (IUSSI2018), August 5-10, 2018 in Guarujá, Brazil.

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Stressing out the honeybee blood-brain barrier

Author(s):
Amalie Strange, Amalie Strange , Tyler Quigley , Gro Amdam
Institution(s):
School of Life Sciences, Arizona State University, Arizona, USA; School of Life Sciences, Arizona State University, Arizona, USA ; School of Life Sciences, Arizona State University, Arizona, USA ; School of Life Sciences, Arizona State University, Arizona, USA
Aging and parasitic load are both stressors associated with extreme behavioral changes in honeybees. Although these behaviors may be partially explained by degradation of neuronal function, dysfunction of the glial blood-brain barrier may also be involved. First, we demonstrate how Varroa mite load during development influences the integrity of the blood- brain barrier. Next, we show how blood-brain barrier integrity changes due to aging and age reversal. This work has broad implications for social insect research; knowledge about the honeybee blood-brain barrier can inform those interested in everything from pollinator conservation to decoding miniature brains.
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